Faculty

Aitor Aguirre

(Department of Biomedical Engineering - Institute for Quantitative Health Science and Engineering), Research in the Aguirre Lab focuses on investigating how tissues and organs respond to injury and regenerate, particularly in the cardiovascular system. To this end, we study development, regeneration and stem cell biology. We use a combination of zebrafish genetics, human stem cell models, biochemistry, functional genomics, metabolomics and tissue engineering approaches. We apply the lessons learned to develop new translational strategies based on cell reprogramming and bio-inspired engineering. aaguirre@msu.edu

Andrea Amalfitano

(Clinical and Translation Science and Microbiology and Molecular Genetics), Feasibility of gene transfer to treat several diseases, both genetic and non-genetic, and to eventually translate that knowledge into the clinical realm-- studying a variety of disease models. amalfit1@msu.edu

Eran Andrechek

(Physiology), The main focus of our research is to examine the mechanisms involved in the development and progression of breast cancer. To do this, we use a combination of bioinformatics and genetic models to understand the heterogeneity present within this disease with the goal of eventually impacting treatment. andrech1@msu.edu

David N. Arnosti

(Biochemistry and Molecular Biology) Eukaryotic gene regulation, transcriptional activation, and repression in Drosophila; function of retinoblastoma tumor suppressor genes in development arnosti@msu.edu

Cindy Arvidson

(Microbiology and Molecular Genetics) Infections with the sexually transmitted pathogen, Neisseria gonorrhoeae (GC, gonococcus) arvidso3@msu.edu

Bill Atchinson

(Pharmacology and Toxicology) Understanding the basis of cellular neurotoxicity especially at synapses atchiso1@msu.edu

Christoph Benning

(Biochemistry and Molecular Biology) Biosynthesis of lipids in photosynthetic membranes, lipid trafficking phenomena involving chloroplasts, engineering of crops and algae for biodiesel production benning@msu.edu

Alison Bernstein

(Translational Neuroscience) Dr. Bernstein’s research focuses on understanding the epigenetic changes that occur in Parkinson’s disease and how alterations to the epigenome by environmental exposures alters Parkinson’s disease risk. Work in the lab ranges from epigenetic studies in human tissue to toxicological studies in animal and cell culture models bernst79@msu.edu

Federica Brandizzi

(Plant Research Lab) How secretory molecules are packaged and which mechanisms regulate the shipment of compounds to the final destination. The mechanisms that lead to the establishment and maintenance of organelles of the secretory pathway fb@msu.edu

Christina Chan

(Biochemistry and Molecular Biology) System biology approaches and tissue engineering platforms, reconstructing signaling and gene regulatory networks; understanding how fatty acids are involved in the development of Alzheimer's disease krischan@egr.msu.edu

Ron Chandler

(Obstetrics Gynecology & Reproductive Bio) Integrated role of chromatin remodeling, epigenetics, and inflammatory signaling pathways in female reproductive tract homeostasis and inflammation-associated gynecologic cancer  Ronald.Chandler@hc.msu.edu

Chen Chen

(Animal Science) Dr. Chen Chen's lab focuses primarily on understanding the regulatory roles of small, non-coding RNA pathways in genome defense and germ cell development. chen2@msu.edu

Tim Collier

(Translational Neuroscience) Utilizes primary cell culture, rat and nonhuman primate models to study mechanisms of central nervous system aging, neurodegenerative diseases and the relationship between the two.  Current work emphasizes etiology and experimental therapeutics related to Parkinson’s disease. Current projects include collaborations in adult stem cell biology, neurobiology of aging, neural growth factor gene therapy, and re-purposing drugs for Parkinson’s disease collie69@msu.edu

Susan Conrad

(Microbiology and Molecular Genetics) Mechanisms by which estrogen and antiestrogens regulate the cell cycle in human breast cancer cells conrad@msu.edu

Chris Contag

(Biomedical Engineering and Microbiology and Molecular Genetics) The Contag lab has developed and used noninvasive imaging approaches to reveal molecular processes in living subjects, to understand host pathogen interactions, to advance diagnostic and therapeutic strategies for cancer, and to reveal the nuances of stem cell engraftment and expansion contagch@egr.msu.edu

Bryan Copple

(Pharmacology and Toxicology) The research in my laboratory is focused on understanding the role of the immune system and hypoxia in the development of liver disease copple@msu.edu

Scott Counts

(Translational Neuroscience) Molecular pathogenic mechanisms of selective neuronal vulnerability in AD. Specific topics of interest include gene regulation within vulnerable projection neurons of cholinergic basal forebrain, noradrenergic locus coeruleus, and glutamatergic medial temporal lobe circuits, differential gene regulation in familial and sporadic AD, mechanisms of neurogenetic protection during AD progression, and the discovery of potential cerebrospinal fluid AD biomarkers scott.counts@hc.msu.edu

Paul Coussens

(Animal Science) Molecular pathogenesis laboratory focuses on the pathogenesis of Mycobacteria coussens@msu.edu

Brad Day

(Plant Pathology) Molecular-genetics of innate immunity in plants bday@msu.edu

Dean DellaPenna

(Biochemistry and Molecular Biology) Biochemical genomics, quantitative genetics and genome wide association mapping of dietary micronutrients in plants. Genomics of medicinal plant metabolism. Synthesis and function of lipid soluble antioxidants in plants dellapen@msu.edu

Andrea Doseff

(Physiology)  Regulatory gene and protein networks of immune cell fate and apoptosis; anti-inflammatory and anti-carcinogenic mechanisms of phytochemicals; phytochemical target identification; the role of cell death regulators in immune-regulation and immune-oncology; foods for health doseffan@msu.edu

Daniel Ducat

(Biochemistry and Molecular Biology) Molecular and synthetic biology approaches for the study of cyanobacterial core metabolism and redirection of photosynthetic pathways for the production of 'green' fuels and commodity products; mixed cyanobacteria-heterotroph microbial consortia ducatdan@msu.edu

Yann Dufour

(Microbiology and Molecular Genetics) Elemental rules that govern emergent group behaviors leading to the successful establishment of bacterial communities inside a host or in open environments. We are particularly interested in the relationships between bacterial chemotaxis, cell-to-cell communication, and the early stage of biofilm formation dufourya@msu.edu

Susan Ewart

(Large Animal Clinical Sciences) Mechanisms of allergic and airway diseases in humans and animal models--identifying genetic, epigenetic, and environmental risk factors for asthma and related allergies EWART@CVM.MSU.EDU

Eva Farre

(Plant Biology) Our goal is to understand how circadian clocks work and why they play such a key role in growth and development. We study the regulation and role of circadian rhythms in plants and alga farre@msu.edu